The book “Essentials in Hematology and Clinical Pathology” emphasizes on building a strong foundation of both concepts. Hematology is one of the rapidly expanding fields of medicine. Understanding hematology requires insight into the applied physiology and the pathophysiologic basis of these diseases in the context of relevant clinical features which is often neglected. Clinical pathology section of the book deals with both hematological and nonhematological laboratory investigations done in routine practice. The book has been organized into four sections namely disorders of red cells, disorders of white cells, disorders of hemostasis and clinical pathology. This book some key features are: (i) Molecular basis of common hematological disorders. (ii) About 135 illustrations, 27 photomicrographs, 18 photographs and 146 tables have been provided to facilitate easy and quick learning. (iii) A summary of the important points at the end of each chapter. (iv) Essay questions, short note questions and 351 MCQs to encourage self evaluation of the important concepts by the students. (v) Recent WHO classification (2008) of tumors of hematopoietic and lymphoid tissues. The textbook will provide a foundation to the students in hematology and clinical pathology and improve their understanding of the subject.